• ‘¤Ž‹ŠoŒo˜H‚É‚¨‚¯‚éGluR2/3‚Ì•ª•z

(Distribution of AMPA-type Glutamate Receptor GluR2/3 Along the Ventral Visual Pathway in the Macaque.)

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‰ÈŠw‹ZpU‹»Ž–‹Æ’cí—ª“IŠî‘bŒ¤‹†u”]‚ð’m‚év‚̃Vƒ“ƒ|ƒWƒEƒ€h”]_Œo‰ÈŠw‚̍Őæ’[1998hiç—¢ƒ‰ƒCƒtƒTƒCƒGƒ“ƒXƒZƒ“ƒ^[A–L’†j 1998.12

@@@Glutamate receptors play a crucial role in information transmission through thalamocortical and corticortical pathways. An immunohistochemical analysis was conducted for the distribution of Glu2/3 immunoreactivity along the ventral visual cortical pathway in Japanese monkeys(Macaca fuscata). Distinct cellular, laminar and regional distribution patterns were found. GluR2/3 immunoreactive cells were distributed mainly in layers 2,3,5 and 6 as well as layer 4B in V1, and were mostly pyramidal cells. Positive cells in layers 2/3 of V1 and V2 form clusters or stripes and corresponds to cytochrome oxidase blobs or stripes in V1 or V2, respectively. Regionally, GluR2/3 immunostaining density was lower in V1 than in the inferior temporal area. In GluR2/3 immunostained sections, V1/V2 border and TE/PR vorder can be clearly demarcated. This unique distribution pattern of GluR2/3 may at least partially contribute to the functional diversity of specific neuronal circuits or different visual areas.


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