Orbitofrontal neuronal activity to accompany with operant conditioned error response.
Ishikawa, T., Tanaka, Y., Miyazawa, T., Fujita, I.*, Nishino, H.* and Oomura,
J. Physiol. Soc. Japan 48: 277
Dept. Physiol., Nihon Univ. Sch. Med., Itabashi, Tokyo 173
*Dept. Biol. Control System, National Inst. Physiol. Sci., Okazaki 444.
Orbitofrontal neuronal activities of the monkey cortex in visual discrimination task were studied. Responded behavior were required to press a bar repeatedly (FR=30) for food on red cue light and continuous bar pressing to avoid an electric shock to the neck skin on green cue light. Of the 123 units in left orbitofrontal cortex, about 30% showed a phasic increase in activity on the red and green light cue, and about 30% showed tonic increase on red light cue and phasic decrease on green light cue. Other 20% showed difference in activities on each cue, and 10% showed no response. In reinforcement and testing responses, the monkey occasionally showed error response to the conditioned error response to the cue light stimulus. The firing activities of some neurons corresponded to the conditioned error response. It was assumed possible that some neurons in the orbitofrontal cortex were related with the behavior.