第32回日本神経科学大会

会期:2009.9.16-18
会場: 名古屋国際会議場

サルV1における方位選択性細胞の空間配置:2光子カルシウムイメージングによる可視化
Arrangement of orientation selective neurons in monkey V1 revealed by in vivo 2-photon calcium imaging
演題番号 : O2-J2-4 一般口演 発表日:2009.9.17

池添 貢司(Koji Ikezoe):1 森 理也(Yoshiya Mori):1 喜多村 和郎(Kazuo Kitamura):2,3 田村 弘(Hiroshi Tamura):1,3 藤田 一郎(Ichiro Fujita):1,3 

1:大阪大院・生命機能(Grad Sch Frontier Biosci, Osaka Univ, Toyonaka, Japan) 2:東京大院・医(Grad Sch Med, Univ of Tokyo, Tokyo) 3:CREST, JST, Toyonaka, Japan

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At the macroscopic level, the preferred orientation of neurons in the monkey primary visual cortex (V1) is systematically mapped across the cortical surface around pinwheel centers. However, how smoothly preferred orientation shifts across the map at the cellular level, which is necessary to consider the function and development of the map. Here, we describe the orientation map at the single-cell level by using in vivo 2-photon calcium imaging in monkey V1. We found that nearby neurons preferred a similar orientation in all 8 recorded regions (< 250 μm x 250 μm) and that the preferred orientation difference increased with distance between neurons. However, a significant fraction of nearby neurons preferred different orientations by more than 60° in 6 of the 8 regions. This additional point argues that orientation map in monkey V1 can also has coarse transitions at the cellular level, meaning that the location and preferred orientation of neurons are less correlative than previously thought.